Abstract
BackgroundEpithelial-myoepithelial carcinoma is an extremely rare disease that usually occurs in the parotid gland but can occur in a variety of sites such as the nasal cavity, paranasal sinus, and base of the tongue.Case presentationWe report a rare case of epithelial-myoepithelial carcinoma, which developed in the subglottic region. A 78-year-old Korean woman visited our hospital complaining of hoarseness, which had developed 1 month previously. Flexible laryngoscopy showed a round mass that blocked approximately 80 % of the tracheal diameter. Complete excision of the mass was carried out under general anesthesia, using a transoral approach. Epithelial-myoepithelial carcinoma was diagnosed following immunohistochemical analysis.ConclusionsWe report a rare case of epithelial-myoepithelial carcinoma that occurred in the subglottic region. To the best of our knowledge, only one other case has been reported since this disease was first identified approximately 40 years ago.
Highlights
Epithelial-myoepithelial carcinoma is an extremely rare disease that usually occurs in the parotid gland but can occur in a variety of sites such as the nasal cavity, paranasal sinus, and base of the tongue.Case presentation: We report a rare case of epithelial-myoepithelial carcinoma, which developed in the subglottic region
We report a rare case of epithelial-myoepithelial carcinoma that occurred in the subglottic region
We report a case of epithelial-myoepithelial carcinoma that developed in the subglottic region, together with a literature review
Summary
Epithelial-myoepithelial carcinoma is an extremely rare disease, first reported by Donath et al in 1972 and officially classified by the World Health Organization in 1991 [1,2,3]. Epithelial-myoepithelial carcinoma comprises two cell groups with distinct features, which are the key to diagnosis. It usually develops in major salivary glands such as the parotid gland, but infrequently occurs in the maxillary sinus, trachea, and larynx [2, 4, 5]. Epithelial-myoepithelial carcinomas in the subglottic region are very rare and to the best of our knowledge only one case has been reported to date [6]. We report a case of epithelial-myoepithelial carcinoma that developed in the subglottic region, together with a literature review.
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