Abstract
Periapical inflammation was induced in monkeys by removing the pulp tissue and leaving the root canals open for varying periods of up to 360 days. Eighteen permanent and 20 primary teeth which had developed periapical inflammation were used for these ex-periments. A similar number of untreated contralateral teeth served as controls. Epithelial cells in the shape of round and elongated islands located in the periodontal membrane were seen in all sections. In the control teeth the average distance from the cementum to the epithelial islands was largest in the marginal third of the periodontal membrane of both primary and permanent teeth. The number of epithelial islands containing more than seven cells was also largest in this area. In the experimental teeth the average distance from the cementum to the epithelial islands and the number of epithelial islands containing more than seven cells were largest in the apical third of the periodontal membrane. About 50 % of all the epithelial islands were located in the marginal third of the periodontal membrane in both control and experimental teeth.
Published Version
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