Epistaxis and persistent sneezing in a Labrador Retriever dog with poorly differentiated invasive nasal squamous cell carcinoma

Abstract

A Labrador Retriever was presented to University Veterinary Hospital, Kokkala with the complaint of nasal bleeding and sneezing for the last one month. Occasional left-unilateral epistaxis, persistent sneezing and facial swelling were the characteristic clinical features. Radiograph revealed mild rarefaction of bones at the cranial tip of maxilla. Biopsy and histopathology revealed pleomorphic squamous epithelial cells with feeble intercellular bridges, poor keratinization, prominent nucleoli and mitotic figures. This article reports a case of invasive nasal squamous cell carcinoma in a dog with epistaxis, persistent sneezing and facial swelling.