Abstract

Backgorund: Sinonasal inverted papilloma (SIP) is a benign tumor of the nasal cavity and sinus. It is characterized by aggressive malignant transformation and a high rate of recurrence. Inadequate removal of the tumor during surgery is one of the most significant contributors to recurrence. SIP has been reported to rarely occur in conjunction with Squamous Cell Carcinoma (SCC) invading the lacrimal drainage system and the orbit. The mechanism of this secondary SCC transformation has yet to be explained. Case presentation: Herein, the authors present the case of a 66-year-old woman with a rapidly enlarging sinonasal inverted papilloma with secondary squamous cell carcinoma of the right nasal cavity presenting with epiphora. Conclusions: Nasolacrimal duct obstructions require a thorough examination as it may hide a malignant pathology.

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