Abstract
Although the central nervous system (CNS) of gastropods has been used as a model for studying neurocommunications and related immunohistochemical studies, there is scanty information on histochemical alterations in neuronal cells due to metal pollution. This study was designed to investigate neuronal alterations in cerebral ganglia intoxicated with mercuric chloride (HgCl2) and cadmium chloride (CdCl2)in terrestrial gastropods slug S. maculata. Histochemically acidic and neutral mucosubstances of neuronal cells were found directly proportional to exposure duration. The glycogen moiety in the neuronal cells was significantly decreased. Hyperplasia was found to be significant in neuronal cell with increased nuclear diameter. Histomorphological and neurochemical alterations were more prominent following HgCl2 than CdCl2 intoxication.
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