Abstract
Two male children (aged 11 and 7 years, respectively) received intramuscular injections of procaine benzylpenicillin 650 000 U and 600 000 U twice daily for streptococcal infection syndrome and acute tonsillitis, respectively. Convulsions, unconsciousness, facial cyanosis, upward deviation of the eyes appeared after the tenth and the third intramuscular injections, respectively. Intramuscular injections of dexamethasone 5 mg and oxygen inhalation through nasal tube were given immediately and the symptoms were improved within 1 min. No positive signs were found on the physical examinations and no abnormal findings were detected by brain CT, EEG and blood biochemical tests. Both patients recovered after treatment with other antimicrobial drugs and the convulsion did not occur at 1 year of follow-up. Key words: Procaine benzylpenicillin; Epilepsy; Children
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