Epilepsy and multiple sclerosis: Clinical, radiological, electrophysiological and neuropsychological aspects

Abstract

Multiple sclerosis (MS) is a chronic autoimmune demyelinating disease of the central nervous system. Epilepsy is three times more frequent in patients with MS when compared to the general population. Focal and focal-to-bilateral seizures are the most frequent ones although they can be misdiagnosed as paroxysmal demyelination events causing a delay in diagnosis and treatment. This study aims to investigate clinical, radiological, electrophysiological and neuropsychological aspects between epileptic MS patients and non epileptic MS patients.