Epigenomic landscapes and their relationship to variation, fitness, and evolution

Abstract

Doctor Tan’s paper insightfully describes how epigenomic investigations of twins can help clarifying the mediation between environmental pressures, the genome, and behaviour. Here, I will expand on two emerging implications and their connections to the twin method. The first proposition deals with the transgenerational inheritance of epigenetic marks. The second examines the relationship between DNA methylation (DNAmeth) and mutation rate (MR), and their evolutionary implications.