Abstract
Epigenetics is the science of biology that studies gene expression changes, which are not caused by changes in DNA sequence, but are also inherited. The molecular basis of epigenetics is a complex phenomenon and determines when and how certain genes are activated. Cancer is characterized as a disease in which cells reproduce uncontrollably and then spread. Cancer is a multifactorial complex disease caused by the accumulation of genetic and/or epigenetic changes. Epigenetic mechanisms include DNA methylation, histone modifications, and noncoding ribonucleic acid regulation. Epigenetic mechanisms affect the tumor behavior and thus the clinical course. Being a biomarker that will determine the diagnosis, treatment and prognosis will enable its use in the diagnosis and treatment of many cancers in the future. We believe that future studies on the relationship between epigenetic mechanisms and cancer will be hope for cancer treatment.
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