Abstract
The Human Genome Project, declared complete in 2003, elucidated the sequence of our genome. Researchers are now learning that another level of information—the epigenome—controls gene expression in part by controlling access to DNA. The gene-reading machinery is blocked when methyl molecules bind to DNA or histones. Conversely, when acetyl molecules bind to histones, DNA becomes less tightly wound and genes become available for transcription. The pattern of these chemical tags can be copied across cell divisions and may even be passed on to an individual's offspring. However, because acetylation and methylation are driven by cell signals, the epigenome is dynamic, enabling it to respond to the environment. Thus, epigenetic tags in a cell lineage can change over the course of an individual's lifetime, even leading to differences between identical twins. This feature focuses on multimedia resources that can be used in teaching epigenetics at the undergraduate and secondary level; several hands-on activities also are included.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
