Abstract
Ongoing research is continuously discovering the role of epigenetics in a various human diseases and disorders. If every single cause and effect of the different combinations of genes could be mapped, and if the gene's state could be reversed to keep the good while eliminating the bad, then epigenetics could cure cancer, slow aging, stop obesity; prevent and treat dental problems. Dental field can greatly benefit from latest research in this area. There could be range of opportunities for diagnosis, treatment and prevention. Potential research of epigenetics for oral health includes the inflammation and immune responses that causes periodontitis and the development of oral malignancies. There is possibility to doze off body's response to oral disease to prevent loss of teeth and protect dental implants.
Highlights
Ongoing research is continuously discovering the role of epigenetics in various human diseases and disorders
Epigenetics is the study of changes in gene function that are mitotically and/or meiotically heritable and that do not entail a change in DNA sequence
Ongoing research is continuously discovering the role of epigenetics in a various human diseases and disorders
Summary
Waddington during the mid-twentieth century have evolved into the field of epigenetics. The term epigenetics, which was coined by Waddington in 1942, was derived from the Greek word “epigenesis” which originally described the influence of genetic processes on development [2]. During the 1990s there became a renewed interest in genetic assimilation. This lead to elucidation of the molecular basis of Conrad Waddington's observations in which environmental stress caused genetic assimilation of certain phenotypic characteristics in Drosophila fruit flies. Mechanisms related to these types of changes [3]. The renewed interest in epigenetics has led to new findings about the relationship between epigenetic changes and a host of disorders including various cancers, mental retardation associated disorders, immune disorders, neuropsychiatric disorders and pediatric disorders
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