Abstract
Epidermolysis bullosa (EB) includes a number of forms of diseases characterized by recurrent blistering as a result of structural weakness, fragility of the skin and some other tissues. All forms of EB are quite rare, the total percentage and prevalence of this disease in the United States is about 19 per 1 million newborns. Clinical manifestations vary widely, from localized blisters on the hands and feet to generalized rashes throughout the skin and oral mucosa, as well as lesions of many internal organs. Diagnosis and treatment are complex and do not always lead to satisfactory results.
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