Abstract

The term Epidermolysis Bullosa (EB) was proposed in 1886 and refers to mechanobullous diseases which are caused by mutations in various structural proteins of skin and presents 1 as blistering of skin following minimal mechanical trauma. The disease severity varies and there are some types that affect only limited areas on body, whereas others can be severe enough to cause involvement of generalized skin surface along with mucosa, badly affecting the quality of life 2 of patients as well as their families.

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