Abstract
Sarcomatoid carcinoma is an unusual and aggressive variant of squamous cell carcinoma, which frequently recurs and metastasizes, therefore requiring accurate diagnosis. A 62-year-old man exhibited an increase in volume involving the face, palate, and right rhinopharynx. An incisional biopsy of the lesion was performed with the hypothesis of malignant neoplasm. Microscopic examination revealed malignant epithelial neoplasia characterized by intense proliferation of cells showing cellular and nuclear pleomorphism, hyperchromatic and vesicular nuclei, evident nucleolus, and mitotic figures, sometimes forming nests and cords of epithelial cells and showing an interlaced sarcomatoid fusiform pattern. The patient was referred to a specialized center for treatment and follow-up.
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