Abstract

Human papillomavirus (HPV) is one of the more common viral causes of mucocutaneous lesions in HIV positive individuals. The incidence of cutaneous warts in adult and paediatric HIV infection is estimated to be up to 27%. These warts are often multiple, large, rapidly growing, refractory to treatment, and may result in considerable morbidity. Epidermodysplasia verruciformis (EV)-like presentations have been reported and epidermal dysplasia progressing to in situ carcinoma has also been reported within the warts of HIV positive individuals. There is evidence that immune status may influence the HPV types harboured by skin lesions. However, there are relatively few studies in which the spectrum of HPV types present in HIV-associated cutaneous lesions have been analysed. In this study we present the results of HPV typing from a series of lesion from HIV infected individuals.

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