Epidermodysplasia Verruciformis Associated with Natural Killer/T Cell Lymphoma

Abstract

Epidermodysplasia verruciformis (EV) is an extremely rare genodermatosis characterized by verruca plana like warts that may undergo malignant transformation.1,2 We report a 12-year-old boy who had hypopigmented smooth macules and wart-like lesions for 10 years (Figure 1). He was referred for facial swelling and erythema of his right cheek. The right nasal cavity was completely filled with a smooth mass. A biopsy specimen obtained from the nasal cavity revealed high-grade malignant tumor infiltration (Figure 2).