Abstract

IN adult mammals the epidermal cell population is in a steady state—continuous cell loss by keratinization is balanced quantitatively by new cell production in the basal layer. We have found that the turnover time of albino guinea-pig epidermis (time required for the replacement of a number of cells equal to that present in the basal, spinous and granular layers) differed from that reported by Platt1 and also from that found for other mammals 2–5.

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