Epidermal-cell population changes produced by exposure to 2,300 R.

Abstract

HomeRadiologyVol. 103, No. 1 PreviousNext Radiation BiologyEpidermal-Cell Population Changes Produced by Exposure to 2,300 RJohn O. Archambeau, Anne Gerber, Rafik Ayoub, Harry J. BrenneisJohn O. Archambeau, Anne Gerber, Rafik Ayoub, Harry J. BrenneisAuthor Affiliations Department of Therapeutic Radiology Nassau County Medical CenterEast Meadow, N. Y. 11554John O. ArchambeauAnne GerberRafik AyoubHarry J. BrenneisPublished Online:Apr 1 1972https://doi.org/10.1148/103.1.191MoreSectionsPDF ToolsImage ViewerAdd to favoritesCiteTrack CitationsPermissionsReprints ShareShare onFacebookTwitterLinked In AbstractThe histological changes produced by irradiation of a 10 cm (diameter) field on the shoulder of immature swine could be divided into degenerative and regenerative phases. The degenerative phase was characterized by progressive cell loss, increased nuclear volume, and a lower mitotic index. The cell loss was complete or maximal by twenty-one days. The regenerative phase was characterized by discrete islands of proliferating cells, first seen at twenty-one days. These islands increased in diameter; by twenty-eight days they had fused into a re-epithelialized surface which then became hyperplastic. The apparent doubling time of the regenerating phase was 3.3 days.Article HistoryPublished in print: Apr 1972 FiguresReferencesRelatedDetailsCited ByChanges in epidermal radiosensitivity with time associated with increased colony numbersThe British Journal of Radiology, Vol. 74, No. 881Recommended Articles RSNA Education Exhibits RSNA Case Collection Vol. 103, No. 1 Metrics Altmetric Score PDF download