Abstract
Since 1997, researchers in the UK have searched for variant Creutzfeldt-Jacob and other diseases that cause progressive intellectual and neurological deterioration (PIND) by sending a monthly surveillance card to UK pediatricians.
Highlights
Hyperglycemia in more than 50% of acute stroke patients is an independent risk factor for poor outcome
In patients with persistent arterial occlusion, GKI infusion was associated with greater infarct growth
The authors conclude that GKI infusion to treat moderate hyperglycemia in acute ischemic stroke requires further study and is not recommended in routine clinical practice
Summary
Hyperglycemia in more than 50% of acute stroke patients is an independent risk factor for poor outcome. Guidelines recommend blood glucose monitoring but optimal method of management is not established. In the above trial of insulin infusion within 24 hours of stroke, blood glucose was lowered and an increase in brain lactate was attenuated, but cerebral infarct growth was not affected.
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