Abstract
This review summarizes several epidemiological studies of multiple sclerosis (MS) in Russia. The Authors selected the most well-organized population-based studies of MS prevalence and incidence in the huge territory of Russia. These studies were mostly published in Russian language and were unknown to international readers. In the majority of Russian territories MS prevalence ranged from 30 to 70 cases per 100,000 population inhabitants. At most places where the epidemiology of MS had been assessed more than once, an increase in prevalence has been reported over time. Incidence showed fluctuations with an increase in Eastern parts of the country. This increased prevalence despite a relatively stable incidence in the European part of the country may reflect the increased survival of the MS population. Russia as a whole can be considered at medium risk for MS. Significant increase of prevalence rates have been recently reported, especially in Siberia and in the Far East regions of the country.
Highlights
This review summarizes several epidemiological studies of multiple sclerosis (MS) in Russia
Data from some of the studies done in different time periods are presented in the Table and show that there is a general tendency of increasing of MS prevalence almost everywhere in Russia
Recent studies of MS prevalence and incidence at the Far East region show relatively low frequencies with MS prevalence from 11 to 23 cases per 100,000 population [9]. This short review shows that the majority of territories of Russia fall into the medium MS risk zone with a prevalence ranging mostly from 30 to 70 cases per 100,000 population
Summary
This review summarizes several epidemiological studies of multiple sclerosis (MS) in Russia. The traditional view, based on numerous early studies and reviews, is that MS is prevalent in low temperate zones, less common in subtropical zones, and uncommon in tropic zones Both in the Northern and Southern hemisphere the characteristic pattern have been increasing prevalence towards the poles, deviations from this pattern can be seen both in Europe and North America as well as in Australia and New Zealand.
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