Abstract
BackgroundMajor depressive disorder (MDD) is one of the important causes of disease burden in the general population. Given the experiencing rapid economic and social changes since the early 1990s and the internationally recognized diagnostic criteria and interview instruments across the surveys during 2001–2010 in china, the epidemiological studies on MDD got varied results. We performed this meta-analysis to investigate current, 12-month and lifetime prevalence rates of MDD in mainland China.MethodsPubMed, Embase, Chinese Biological Medical Literature database (CBM), Chinese National Knowledge Infrastructure database (CNKI), and the Chinese Wanfang and Chongqing VIP database were searched for associated studies. We estimated the overall prevalence of MDD using meta-analysis.ConclusionsSeventeen eligible studies were included. Our study showed that the overall estimation of current, 12-month and lifetime prevalence of MDD was 1.6, 2.3, 3.3%, respectively. The current prevalence was 2.0 and 1.7% in rural and urban areas, respectively; between female and male, it was 2.1 and 1.3%, respectively. In addition, the current prevalence of MDD diagnosed with SCID (Structured Clinical Interview for DSM-IV) was 1.8% and that diagnosed with CIDI (Composite International Diagnostic Interview) was 1.1%. In conclusion, our study revealed a relatively high prevalence rate in the lifetime prevalence of MDD. For current prevalence, MDD diagnosed with SCID had a higher prevalence rate than with CIDI; males showed a lower rate than females, rural residents seemed to have a greater risk of MDD than urban residents.
Highlights
Major depressive disorder (MDD) is considered to be the most common mental illness, and it is the fourth primary cause of disability with annual total costs to society exceeding $80 billion worldwide [1,2,3,4,5,6]
All of the included studies should meet the following selection criteria: (i) cross-sectional study; (ii) based on general population samples rather than volunteers (iii) participants aged 15 years and over; (iv) cross-sectional study that provided the prevalence of MDD; (v) used a screening instrument in the first phase of the study, such as the Composite International Diagnostic Interview (CIDI), General Health Questionnaire (GHQ)
Our result showed that the current prevalence of MDD in mainland China is lower than in Asia including Japan (2.9%) [39] and in the United States (6.6%) [1]
Summary
Major depressive disorder (MDD) is considered to be the most common mental illness, and it is the fourth primary cause of disability with annual total costs to society exceeding $80 billion worldwide [1,2,3,4,5,6]. China is one of the middle-income countries that has been experiencing rapid economic and social changes since the early 1990s, leading to a huge number of social phenomenon such as mounting rates of divorce, alcohol and illicit drug abuse, fast growing costs of health care, weakening of family ties, increased number of farmers migrating to urban areas for temporary jobs and so on [16] All of these with a major potential impact on mental health in general is depression [17]. Given the experiencing rapid economic and social changes since the early 1990s and the internationally recognized diagnostic criteria and interview instruments across the surveys during 2001–2010 in china, the epidemiological studies on MDD got varied results We performed this meta-analysis to investigate current, 12-month and lifetime prevalence rates of MDD in mainland China
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