Abstract
Recent interest in lupus has expanded various efforts to better define its population burden. The Centers for Disease Control and Prevention coordinated National Lupus Registries that advance our epidemiologic understanding of and methodological approach to lupus. More accurate estimates of incidence and prevalence of lupus in the United States have shown significant burden among racial/ethnic minority groups. These efforts underscore the need to better coordinate future studies, particularly as it relates to case definition. These efforts confirm the significant burden of systemic lupus erythematosus, particularly in younger minority populations. Experience from these studies could also inform other surveillance efforts in lupus, as well as other medical conditions for which similar methodologic challenges exist.
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