Abstract
Multi-drug resistant (MDR) Enterobacteriaceae are on the increase worldwide and their spread has become a global challenge. Escalating the challenge is the possibility that many of these are Carbapenemase-producing Enterobacteriaceae (CPE). This further complicates patient management. The magnitude of MDR-CPE in many developed settings has been reported, however, there is paucity of data from resource limited settings.
Highlights
Multi-drug resistant (MDR) Enterobacteriaceae are on the increase worldwide and their spread has become a global challenge
We evaluated the epidemiology of MDR-Carbapenemase-producing Enterobacteriaceae (CPE) of clinical origin in South Western Uganda
Isolates found to be MDR were screened for carbapenem susceptibility/ resistance phenotypically by Kirby Bauer disc diffusion method following EUCAST guidelines and genetically using the multiplex real-time Polymerase Chain Reaction (RT-PCR)
Summary
Multi-drug resistant (MDR) Enterobacteriaceae are on the increase worldwide and their spread has become a global challenge. Escalating the challenge is the possibility that many of these are Carbapenemase-producing Enterobacteriaceae (CPE). The magnitude of MDR-CPE in many developed settings has been reported, there is paucity of data from resource limited settings
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