Abstract
Introduction: According to the importance of knowledge about incidence and mortality of oral cavity and lip cancer in health planning, this study was performed with the aim of investigating the incidence and mortality rate of oral cavity and lip cancer and its relation with the Human Development Index in the world in 2012. 
 Methods: The study was conducted based on data from the world data of cancer and the World Bank (including the HDI and its components). Data about the age-specific incidence and mortality rate (ASR) for every country in 2012 were getting from the global cancer project. To analyze data, correlation tests between incidence and death rates, and HDI and its components were employed with a significance level of 0.05 using SPSS software.
 Results: In 2012, 300373 cases of oral cavity and lip cancer and 145353 cases of death from it have occurred in the world. A positive correlation of 0.221 was seen between the standardized incidence rate of oral cavity and lip cancer and HDI but this correlation was not statistically significant (p=0.114). On the other side, a correlation of 0.295 was seen between the standardized mortality rate of oral cavity and lip cancer with HDI that this correlation was statistically significant (p<0.001).
 Conclusion: The incidence and mortality of oral cavity cancer is high in the Asian countries especially south eastern of Asia. Performing preventive plans in high incidence and mortality rate regions and also obtaining etiological studies in these regions is recommended for diagnosing the causes of high incidence and mortality rates.
Highlights
According to the importance of knowledge about incidence and mortality of oral cavity and lip cancer in health planning, this study was performed with the aim of investigating the incidence and mortality rate of oral cavity and lip cancer and its relation with the Human Development Index in the world in 2012
The concern about lip and oral cavity area is related to high incidence of malignant tumors in this areas compared to other areas of head and neck. complications and mortality which occur from squamous cell carcinoma diagnosis which is a the diagnosed tissue, that can be found 40% in lip and oral cavity, 25% in the larynx and 15%in the throat with a low incidence in oral area (Ribeiro et al, 2015)
The results of this study showed that the highest standardized incidence rate of lip and oral cavity cancer is related to Papua New Guinea, Maldives, Sri Lanka, Pakistan and Hungary
Summary
According to the importance of knowledge about incidence and mortality of oral cavity and lip cancer in health planning, this study was performed with the aim of investigating the incidence and mortality rate of oral cavity and lip cancer and its relation with the Human Development Index in the world in 2012. Data about the age-specific incidence and mortality rate (ASR) for every country in 2012 were getting from the global cancer project. Results: In 2012, 300373 cases of oral cavity and lip cancer and 145353 cases of death from it have occurred in the world. A positive correlation of 0.221 was seen between the standardized incidence rate of oral cavity and lip cancer and HDI but this correlation was not statistically significant (p=0.114). A correlation of 0.295 was seen between the standardized mortality rate of oral cavity and lip cancer with HDI that this correlation was statistically significant (p
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