Epidemiology, diagnosis and treatment of female breast cancer in Suqian

Abstract

Objective To investigate epidemiology, diagnosis and treatment of female breast cancer in Suqian, and provide the basis for the prevention, screening and accurate treatment for them. Methods The clinical data of 7 043 patients with breast cancer in Suqian area were collected. The relationships among pathological types, disease stage, annual incidence, annual mortality, incidence ratio of urban to rural areas, left for treatment, economic status and treatment were analyzed. Results In the 7 043 patients with breast cancer, 2 445 cases were from 41 to 50 years old, 1 349 cases were from 51 to 60 years old. 4 326 cases were in urban area, accounting for 61.42% of newly diagnosed cases in 7 years; 2 717 cases were in rural area, accounting for 38.58% of newly diagnosed cases in 7 years. Annual incidence were 10.98/100 000 to 22.83/100 000, annual mortality of the total population were 3.47/100 000 to 11.22/100 000, death ratio between urban and rural was 1∶2.18. The rate of patients which completed treatment or was still in treatment was 31.48%, the rate of patients which did not complete treatment or refused to continue treatment was 48.89%. Breast-conserving treatment rate of left for treatment was 25.74%, and that was 4.96% in Suqian. Patients of I-II stage breast cancer in urban areas accounted for 28.47%, while those in rural area accounted for only 15.62%. One year disease-free survival (DFS) and overall survival (OS) of all patients were 100%, 3-year DFS and OS were 78.19%, 86.37% respectively; 5-year DFS and OS were 66.37%, 73.16% respectively. Conclusions The increase of annual incidence and mortality of breast cancer should be paid more attention by medical workers in Suqian area and primary prevention and screening need to be strengthened. The incidence of urban patients was higher than that of rural patients, but the mortality in rural areas was higher than that in urban areas. The number of patients in urban area who completed the treatment was higher than that of rural patients. In addition to annual incidence and annual mortality which are not standardized, breast-conserving rate was still very low, so doctors working on breast cancer diagnosis and treatment in Suqian should strengthen related work. Key words: Suqian; Breast cancer; Epidemiology; Annual incidence; Annual mortality rate