Abstract
The precise frequency of drug-induced lung disease (DILD) is unclear, but the reported number of cases of DILD has been increasing, especially after reports of severe DILD caused by gefitinib in Japan. General risk factors for DILD include current smoking, old age, preexisting lung disease (especially interstitial pneumonia), history of thoracic surgery or irradiation of the lung, and renal failure. There are ethnic differences in the frequency of DILD caused by certain drugs, and genetic factors may partially contribute to this. In addition to classic antineoplastic agents, antirheumatic drugs, interferon, herbal medicine, and molecularly targeted drugs frequently cause DILD. Checkpoint inhibitors can also cause severe interstitial lung disease (ILD) as one of a variety of side effects associated with their immunomodulatory function.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
