Abstract
To describe clinical, histopathological and treatment characteristics of melanoma in a private institution of Bogotá, Colombia, and to identify differences regarding sex and age. Observational, retrospective study. 415 medical records between January 1999 and May 2014 were analyzed. Out of 415 patients, 244 (58.8%) were females and 171 (41.2%) were males with a mean age of 56.1 ±16.2 SD. Superficial spreading melanoma (SSMM) was the main subtype (n=175, 42.7%). Breslow's thickness ≤1mm was predominant, while phototypes II and III were more frequent (n=87, 69.6%). Melanoma was predominantly localized on the head in men (n=83, 50.3%) and in the lower limbs in women (n=89, 36.8%), with a higher frequency of SSMM pattern among patients aged ≤65. Lentigo maligna (LM) was more frequent in patients aged >65 (p<0.001), with a higher number of ulcerated melanomas (p=0.046). A predominance of thin SSMM and fair skin phototypes were found, unlike previous reports that showed acral lentiginous melanoma (ALM) as predominant, which may be caused by local variations related to mixed ethnicity.
Highlights
A statistical significance was found (p
A value less than or equal to 1 mm was observed in 310 patients (79.3%)
When comparing the growth pattern, Lentigo maligna (LM) was the most frequent among in situ MM (49.2%), while Superficial spreading melanoma (SSMM) had the higher proportion of invasive MM (58.2%; p
Summary
The objective of this study is to describe the clinical, histopathological and treatment characteristics of melanoma in a private institution of reference for skin cancer, and to identify differences regarding sex and age. Clinical data (age, sex, phototype based on Fitzpatrick scale I-VI, lesion site, growth pattern, stage, number of nevus, atypical nevus), histopathological data (Breslow index, Clark level, ulceration, mitotic index, regression) and treatment data were assessed.
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