Abstract

Abstract Objectives: to assess the epidemiological profile of congenital and syphilis during pregnancy in residents of São José do Rio Preto in São Paulo State. Methods: ecological study of the epidemiological profile of patients with congenital and gestational syphilis, based on the Sistema de Informação de Agravos de Notificação (Information System for Notifiable Diseases) from 2007 to 2016. Results: there were 396 cases of syphilis reported in pregnant women and 290 of congenital syphilis. In 2016, the rate of detecting syphilis in pregnant women was 13.2 cases/1,000 live births, while congenital syphilis the incidence rate was 6.5 cases/1,000 live births. For gestational syphilis, 54% of the diagnosis was performed in 2nd or 3rd trimester and 85% were reported at the primary care. Adequate treatment for pregnant women occurred in 96% of the notifications with 52% of partners treated. In congenital syphilis, 82% of the mothers underwent prenatal care. However, 94% of the pregnant women were treated inadequately while 82% of the partners did not receive any treatment. Conclusions: there has been an increase in the number of cases of gestational syphilis in pregnant women and a decrease in the cases of congenital syphilis from 2014. These results showed that the goal of 0.5 case/1,000 live births proposed by World Health Organization is still far from being achieved in this city.

Highlights

  • Syphilis is an infectious disease with chronic evolution and often asymptomatic, caused by the Treponema pallidum bacterium

  • The objective of this study was to assess the epidemiological profile of mandatory notifications of congenital syphilis in pregnant women registered and living in the city in São José do Rio Preto, Brazil, from 2007 to 2016. This is an ecological study, using data contained in the Sistema de Informação de Agravos de Notificação (Sinan) (Information System for Notifiable Diseases) from mandatory notifications of syphilis cases in pregnant women and congenital syphilis in residents in São José do Rio Preto, Brazil, from January 1, 2007 to December 31, 2016

  • All the data from Sinan and Sinasc were collected at the Vigilância Epidemiológica da Secretaria Municipal de Saúde (Epidemiological Surveillance Service at the Municipal Secretary of Health)

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Summary

Introduction

Syphilis is an infectious disease with chronic evolution and often asymptomatic, caused by the Treponema pallidum bacterium. It is estimated that over 11 million new cases of syphilis occur each year worldwide, with high incidence rates specially in Latin America, Africa and Asia.[2] In Brazil, the disease constitutes as a serious public health problem, especially in the maternal and child population.[3,4]. In Brazil, between 2007 and 2016, there has been an increase in the number of notifications and epidemiological rates of syphilis at pregnancy and congenital syphilis. The detection rate was 2.5 cases/1,000 live births in 2007 to 12.4 cases/1,000 live births in 2016. The incidence rate was 1.9 cases/1,000 live births in 2007 and increased to 6.8 cases/1,000 live births in 2016.5.

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