Abstract

Cancer of the cervix is the third most common cancer in women worldwide, more than 85% of the cases occurring in developing countries such as China. In China, since a national cancer registry is already set up but with geographically limited data generated, the burden of cervical cancer is believed to be underestimated. High- risk human papillomavirus (HR-HPV) prevalence among women attending routine cervical cancer screening programs has been shown to correlate well with cervical cancer incidence rates based on independently obtained HPV prevalence data as well as findings for the worldwide cervical cancer burden. Therefore, reviewing data on HR-HPV prevalence in population-based screening studies and hospital-based case studies will be important in the context of better understanding the cervical cancer burden and for the evaluation of the potential impact of HPV vaccination in the country. With the advent of prophylactic vaccines, significant progress is likely to be made in cervical cancer prevention. This article reviews available data on the HPV epidemiology over a 12-year time period (2001-2012) in mainland China under different epidemiological aspects: by age group of study population, by ethnicity, by geographic area, as well as time period. The authors also review the potential acceptability of HPV vaccination among Chinese women.

Highlights

  • Cancer of the cervix is the third most common cancer in women worldwide, with an estimated 529,000 new cases and 274,000 deaths occurring in 2008 (Ferlay et al, 2010)

  • Highrisk human papillomavirus (HR-HPV) prevalence among women attending routine cervical cancer screening programs has been shown to correlate well with cervical cancer incidence rates based on independently obtained HPV prevalence data as well as findings for the worldwide cervical cancer burden

  • Reviewing data on HR-HPV prevalence in population-based screening studies and hospital-based case studies will be important in the context of better understanding the cervical cancer burden and for the evaluation of the potential impact of HPV vaccination in the country

Read more

Summary

Introduction

Cancer of the cervix is the third most common cancer in women worldwide, with an estimated 529,000 new cases and 274,000 deaths occurring in 2008 (Ferlay et al, 2010). More than 85% of the cases occur in developing countries such as China. In China, since a national cancer registry is already set up but with geographically limited data generated, the disease burden of cervical cancer is believed to be underestimated. Reviewing data on HR-HPV prevalence will be important in the context of better understanding the cervical cancer burden in the country. Significant progress has been made in cervical cancer prevention especially with the availability of prophylactic vaccines. HPV vaccination holds a promising future for cervical cancer prevention especially for countries with limited access to screening

13 HR-HPV*
Findings
Conclusions
Full Text
Published version (Free)

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call