Epidemiological features of cervical malignancies in the Altai region

Abstract

Objective: This study aimed to investigate the epidemiological features of cervical malignancies in the Altai region. Material and methods. This study used data from the cancer register of the Altai Regional Cancer Center in Barnaul City. The cancer register records data of approximately 253,000 patients with malignant neoplasms, including 12,259 women with cervical cancer. We evaluated the “rough” (per 100,000 female populations) and standardized (world standard per 100,000 female populations) indicators of morbidity and mortality of cervical malignancies in Altai region within 20 years. The dynamics of the incidence and mortality of cervical cancer was analyzed by year and age groups. Results: For the 1989–2018 period in the Altai region, a significant shift was found in the incidence of cervical cancer, which tends to increase in young population of reproductive age. During the 2008–2018 period, no positive changes were noted in the indicators of early diagnosis, i.e., no changes were found in the proportion of patients diagnosed with stage I and II (%) cervical cancer for the first time and the proportion of patients with stage III and IV (%) cervical cancer. The proportion of women who died from cervical cancer in the structure of oncogynecological diseases in the Altai region exceeds that in the Russian Federation.