Epidemiological features and trends of endometrial cancer: 10 081 cases analysis of 62 hospitals in Guangdong province

Abstract

Objective To explore the epidemiology characteristics of endometrial cancer (EC). Methods We retrospectively analyzed 10081 patients diagnosed with EC from 62 hospitals between 2000 and 2010 in Guangdong province. Results The mean age at diagnosis was 52.8±9.3. The proportion were 19.3%, 64.2%, 16.6% in patients with ages ≤45, >45-60, >60 respectively. From 2000 to 2010, the mean ages at each year were no statistic significance. The number of cases of EC were positively correlated with years(r=0.964, P<0.001). The number of cases of patients with ≤30 years old (r=0.857, P=0.001), ≤35 years old (r=0.866, P=0.001), ≤40 years old (r=0.952, P<0.001), ≤45 years old (r=0.952, P<0.001) were positively correlated with years. The ratios of patients with ≤30 years old (χ2=10.390, P=0.407), ≤35 years old (χ2=11.651, P=0.309), ≤ 40 years old (χ2=17.329, P=0.067), ≤45 years old (χ2=5.154, P=0.881) during these eleven years were no statistic significance. The ratios of type Ⅰ EC at 2000-2010 were no statistic significance. Conclusions EC often present in patients aged from >45-60 years old. The case number of EC showed an increasing trend. However, the proportion of young patients was stable. The endometroid adenocarcinoma was the main histological type of EC. Key words: Endometrial neoplasms/EP