Abstract
Epidemiological, clinical and progressive spectrum of measles cases admitted to „Dr. Victor Babes“ clinical hospital for infectious and tropical diseases, bucharest during the actual outbreak
Highlights
Starting with 2016 Romania had to face an alarming measles outbreak due to the continuous poor vaccination coverage
The total number of patients diagnosed with measles during the analysed period was 632, significantly higher in 2017 compared to 2016 (604 vs. 28) (Fig. 1)
The incidence of measles has been alarmingly increasing in recent years in Romania, especially affecting children aged 1 to 4 years
Summary
Starting with 2016 Romania had to face an alarming measles outbreak due to the continuous poor vaccination coverage. A quarter of the patients (31.3%) had familial contact with a measles case. Almost all of them developed viral complications, 84.1% being diagnosed with interstitial pneumonia. Bacterial pneumonia was diagnosed in 15.0% cases, out of which 45.2% were associated with respiratory failure. The number of patients diagnosed with measles during the last years registered an alarming increase, especially in children under 4 year old, with a high number of complications. We consider it mandatory to apply the vaccination program to ensure an optimal vaccine coverage, useful both in stopping the current outbreak and in preventing future outbreaks. Subacute sclerosing panencephalitis – is a rare but severe complication that appears at a long time from the acute episode (with an average of 7 years), with progressive degeneration of the central nervous system, being lethal in a percentage of 100%
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