Epidemiological, Clinical and Paraclinical Aspects of Cirrhosis at Borgou Departmental University Hospital Center (Benin)

Comlan Albert Dovonou,Fabien Houngbe,Djimon Marcel Zannou,Cossi Angelo Attinsounon,Cossi Adébayo Alassani,Kadidjatou Sake,Angèle Azon-Kouanou,Agossou Romaric Tandjiekpon

doi:10.4236/ojim.2018.82012

Abstract

Objective: To study the epidemiological, clinical and paraclinical aspects of cirrhosis at Borgou Departmental University hospital Center. Methods: This is a retrospective study for descriptive purpose conducted in the Internal Medicine Department. The study population consists of patients hospitalized in the Internal Medicine Department during the period from 1st January 2009 to 31st December 2016. Results: The frequency of cirrhosis was 1.35%. The sex ratio was 3.76. The average age of patients was 45.22 ± 15.23 years old, with a range from 15 to 82 years. There is a post hepatitis Bcirrhosis predominance in 87.5% of cases, followed by alcoholic cirrhosis in 21.59% of cases. The complications of cirrhosis are dominated by ascites (78.4%) and jaundice (52%). Conclusion: Cirrhosis is a condition that is wide spread. The hepatitis B virusis the main cause of liver cirrhosis followed by alcoholism. Ascites is the most encountered complication. It’s very important now to educate the populations for a behaviour change and to promote vaccination against viral hepatitis.

Highlights

Hepatic cirrhosis is a pathology characterized by the disorganization of liver architecture attributable to hepatocytes destruction since the hepatocellular regeneration remains in form of regeneration nodules with the presence of fibrosis
The goal of this study is to describe the epidemiological, clinical and paraclinical aspects of cirrhosis in Borgou Departmental University hospital Center
Hepatitis B virus is the main cause of hepatic cirrhosis followed by chronic alcoholism

Summary

Introduction

Hepatic cirrhosis is a pathology characterized by the disorganization of liver architecture attributable to hepatocytes destruction since the hepatocellular regeneration remains in form of regeneration nodules with the presence of fibrosis. In United State, Cirrhosis prevalence is 0.15% and represents respectively the tenth and the twelfth cause of death in men and in women, killing about 35,000 people every year [2]. In Europe, almost 170,000 of death related to cirrhosis are registered per year and represent 1.8% of all causes of death [3]. In Africa, the hospital prevalence of cirrhosis is at 7.02% in 2012 in Togo [4] and 2.35% in 2008 in Mali [5]. No studies on hepatic cirrhosis have been performed in northern Benin. The present study was initiated to identify the different and the most common cause of hepatic cirrhosis. The results of this study will help prevent liver cirrhosis. The goal of this study is to describe the epidemiological, clinical and paraclinical aspects of cirrhosis in Borgou Departmental University hospital Center

Patients and Methods

Results

Discussion

Findings

Conclusion