Abstract

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has wreaked havoc on millions of people around the world. Although China quickly brought the Coronavirus disease (COVID-19) under control, there have been several sporadic outbreaks in different regions of China since June 2020. This article described the chronological nosocomial COVID-19 infection events related to several sporadic outbreaks of SARS-CoV-2 in different regions of China. We have reported epidemiological characteristics and management measures of sporadic nosocomial COVID-19 infections from June 2020 to June 2021 and specially focused on the domestic COVID-19 breakthrough infection in China, such as domestic COVID-19 breakthrough infection—a vaccinated healthcare professional working in the isolation ward of a designated COVID-19 hospital.

Highlights

  • The outbreak of the Coronavirus-2019 (COVID-19) virus was first reported in Wuhan, China, in December 2019

  • This study provides us with an inspiring vision regarding the current COVID-19 pandemic

  • The main findings of sporadic nosocomial COVID-19 infections from June 2020 to June 2021 are listed below: [1] the importance of rolling out an overall nucleic acid test campaign to all staff in healthcare settings is a crucial part of the COVID-19 surveillance; [2] the case of coronavirus transported onto the workplace warns us that the current hospital disinfection concept urgently requires updating, especially in designated hospitals, and there is an urgent demand of the management of staff accompanying patients in nondesignated hospitals; [3] The phenomenon about COVID-19 vaccine breakthrough infection deserves our great attention

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Summary

Introduction

The outbreak of the Coronavirus-2019 (COVID-19) virus was first reported in Wuhan, China, in December 2019. The COVID-19 pandemic led China to quarantine the population to protect them [1]. Chinese authorities decided to adopt extraordinary measures to contain and limit the spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus. From January 1, 2020, to April 8, 2020, >8,000 patients with COVID-19 were hospitalized, and the Chinese government imposed the Wuhan lockdown on January 23, which ended on April 8, 2020. With the COVID-19 epidemic quickly under control in the early stages of 2020, importing the SARS-CoV-2 virus could pose great challenges to the control and prevention of nosocomial COVID-19 infection in healthcare settings. Our previous report showed the impact of the novel

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