EPIDEMIOLOGICAL ASPECTS OF SEPSIS

Abstract

Last decades a sepsis problem attracts the increased interest in the world community. In spite of definite achievements of modern fundamental and clinical medicine, sepsis as before is characterized by significant dissemination and high lethality. The problems of sepsis spread in various countries are discussed. It is shown that annually million cases of generalized purulent-septic infections are diagnosed. Steady sepsis increase is registered in industrially developed countries. Share of severe sepsis in pathology structure varies from 2 to 43% in different territories. Sepsis still remains among leading causes of human death being characterized by essential hospital lethality (from 30,6 to 80,4%). The patient categories belonging to high risk groups of sepsis development are shown. Special attention is directed to epidemiological manifestations of this pathological syndrome in pediatrics. Features of etiologic spectrum of the sepsis causative agents, increasing etiological importance of multi-resistant bacteria (Pseudomonas aeruginosa, Klebsiella pneumoniae, Acinetobacter spp., MRSA, VRE, etc.) are demonstrated. In consideration of clinical-epidemiological, social and economic significance of sepsis, studying of its epidemiological aspects is the major direction of activities for Public Health services.