Abstract
The burden of tuberculosis is extraordinarily unequal between countries. Incidence rates range from below 10 per 100 000 population in many mainly high-income countries to greater than 300 per 100 000 population in many other mainly low-income and middle-income countries.1 It has not always been so. Countries in Europe, North America, and high-income parts of the Asia-Pacific region had high burdens of tuberculosis in the first half of the 20th century, but achieved rapid rates of decline, particularly after World War 2.
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