Abstract

The aim of this study was to characterize the sociodemographic profile and changes in the metabolic profile of women living with HIV/AIDS. A cross-sectional study of a retrospective cohort was conducted in women with HIV/AIDS treated at the Specialized Care Service (SCS) in Ponta Grossa, Paraná. Between January/2008 and December/2017, data from 111 women were included.

Highlights

  • Infection with the human immunodeficiency virus (HIV) and the follow-up of people living with HIV/AIDS have been, since its discovery in 1983, a major challenge for Brazilian and global public health [1]

  • These results show that there was an increase in weight and other factors considered at risk for the development of metabolic syndrome and cardiovascular events

  • The follow-up variables were collected in two moments, 2008 and 2017, in order to analyze the progression of the disease, namely: Metabolic profile (weight, lipid profile, blood glucose, blood pressure, CD4 counting, viral load and therapeutic regimen: Protease inhibitor (PI), Nucleoside analogue reverse transcriptase inhibitor (NRTI), Non-nucleoside reverse transcriptase inhibitor (NNRTI) and Integrase inhibitor (INI)

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Summary

Introduction

Infection with the human immunodeficiency virus (HIV) and the follow-up of people living with HIV/AIDS have been, since its discovery in 1983, a major challenge for Brazilian and global public health [1]. According to WHO, since the beginning of the epidemic, 76 million people have been infected with the HIV virus worldwide and about 33 million people have died of HIV. 966,058 cases of AIDS were reported in Brazil. In the verification of the gender ratio per year of diagnosis, there were important regional differences in Brazil, and in the Southern region there was a higher proportion of women in the total number of AIDS cases: the gender ratio was 18 men for every ten women. Among women in Brazil, in 2008, the highest AIDS detection rate was observed among women aged 30 to 34 years (37.2 cases/100,000 inhabitants); in 2018, the ranges with the highest detection were those of women between 40 and 44-years-old (20.5 cases/100,000 inhabitants) [3]

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