Epidemiological and diagnostic analyses of 1194 cone biopsies (author's transl)

Abstract

1194 patients of the Department of Gynecology and Obstetrics of the University in Kiel were treated by cone biopsy 1971-1979. In 92 of these cases the cone biopsy was free of pathological epithelium despite positive prefindings. The part of adeno-carcinoma of the cervix was 1.2%. In two control-periods (1971-6/75 and 7/75-1979) the quantity of 16-30 year old women with dysplasia or carcinoma in situ of the cervix was high significantly increased in the last period. The prescription of ovulation inhibitors is due to this tendency as one of other important factors. The average age of patients first treated by cone biopsy decreased from 44 years to 36 in 1971 to 1979. The majority of the carcinoma in situ was completely excised by women below 30 years old. The cases of not free margins increased to 72% with advancing in years. Over the half of patients with not completely removed carcinoma in situ or micro-carcinoma there was no pathological epithelium in the followed exstirpated uterus. The reason for this behaviour may be the hemostasis with high frequency cauterization (coagulation apparates of Semm) since 1977. The number of diagnosis of the carcinoma colli uteri Ia and Ib by cone biopsy was lower in the second control-period compared to the previous period.