Abstract
ObjectivesIn December 2019, coronavirus disease 2019 (COVID-19) emerged in Wuhan City and rapidly spread across the world. The clinical characteristics of affected patients in different regions and populations may differ. Thus, this study aimed to identify the characteristics of the disease to provide an insight about the prevention and treatment of COVID-19.MethodsData on the demographic characteristics and clinical findings of the patients admitted at the First Hospital of Changsha from January 1, 2020 to February 10, 2020 were assessed.ResultsIn this study, there were 8 (3.8%) asymptomatic, 21 (10.0%) mild upper respiratory tract infection (URTI), and 180 (86.1%) pneumonia cases. In total, 47 (22.5%) patients resided in Wuhan, and 45 (21.5%) had recently traveled to Wuhan before disease onset. Moreover, 19 (9.1%) had contact with people from Wuhan, and 69 (33.0%) were family cluster cases. The median incubation period was approximately 6.3 (range: 1.0–20.0) days. Fever and cough were the most common initial symptoms: 99 (49.3%) patients presented with fever, without cough; 59 (29.4%) with cough, without fever; and 33 (16.4%) with both fever and cough.ConclusionThe symptoms of patients with COVID-19 were relatively mild outside Wuhan, and family cluster was a remarkable epidemic characteristic. Special attention should be paid to asymptomatic patients.
Highlights
In December 2019, a cluster of pneumonia cases of unknown etiology was reported in Wuhan, Hubei Province, China [1]
Clinical characteristics and laboratory findings of case series of 209 patients with laboratory-confirmed SARS-CoV-2 infection in Changsha, Hunan province
Recent studies have shown that SARS-CoV-2 has a strong affinity to human respiratory receptors, which indicates that it has a strong capability to infect humans [3]
Summary
In December 2019, a cluster of pneumonia cases of unknown etiology was reported in Wuhan, Hubei Province, China [1]. Recent studies have shown that SARS-CoV-2 has a strong affinity to human respiratory receptors, which indicates that it has a strong capability to infect humans [3]. Since January 2020, COVID-19 has rapidly spread from Wuhan to the entire country. Since January 18, 2021, 98,794 laboratory-confirmed cases of COVID-19 have been documented in Mainland China [7]. COVID-19 has spread in different countries globally, with outbreaks in Spain and Italy, and there is a significant increase in the number of cases in the United States. By January 18, 2021, 93,805,612 infections and 2,026,093 deaths had been reported worldwide, and the numbers can increase further [7]. COVID-19 has become a major public health issue and has been declared as a Public Health Emergency worldwide
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