Abstract

Relevance: Cancer of the uterine body (CUB) is one of the most common types of malignant neoplasms and ranks 6th among the most
 frequently diagnosed cancers in women in the world. Despite the improvement of treatment methods, the incidence and mortality from CUB
 remain high. According to forecasts by the International Agency for Research on Cancer, by 2040, the incidence of CUB is expected to increase
 by more than 50%. Therefore, studying the epidemiological features of CUB is important for developing prevention and treatment strategies.
 The study aimed to analyze the morbidity and mortality from CUB in the female population of Almaty in 2012-2022.
 Methods: The material for the study was data from the information system «Electronic Register of Inpatient Patients» on newly
 identified cases and those registered at the dispensary with a histologically confirmed diagnosis of CUB «Malignant neoplasm of the
 uterine body» (From 54 to ICD-10) of the population of Almaty for the period from 2012 to 2022. Epidemiological indicators were calculated
 per 100,000 female population. The absolute growth, growth rate, and visibility indicators were calculated to analyze changes in intensive
 indicators over time. The database was formed, and the results were statistically processed using Microsoft Excel and the SPSS Statistics
 26 statistical package.Results: There was an increase in the crude incidence of CUB in the female population of Almaty in 2012-2022 by 3.14 times. The incidence
 of CUB increased with age, where the peak incidence was noted in the age group of 60-64 years (58.9±8.68 cases per 100,000 female population
 95% CI = 39.5-78.2). Mortality from CUB decreased from 13.5 cases in 2012 to 1.3 cases per 100,000 female population in 2022 (10.4 times).
 Conclusion: The conducted epidemiological analysis showed the need for further detailed study of the risk factors contributing to the
 occurrence of CUB and improvement of the activities of health services, starting from the primary health care level.

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