Epidemiological & Clinico-pathological Characteristics of Colo-rectal Cancer (Retrospective Analysis)

Abstract

Background and purpose: Colorectal Cancer (CRC) is the third most common cancer worldwide and in Egypt the 7th most common cancer in men and 4th most common cancer in women. It is the second leading cause of cancer-related deaths. So the present study was conducted to identify the epidemiological and clinico pathological features of colorectal cancers as studying these characteristics can improve patients’ survival rates. Patients and Method: This study is a retrospective study that included CRC patients treated at clinical oncology department, Zagazig University Hospital in the duration from 2012 to 2017. Medical records of 385 patients, who were referred to clinical oncology department after proven diagnosis with CRC and underwent colonoscopy, or discovered during emergency laparotomy were collected and analyzed. Results: The highest incidence (19.2%) was in 2017. The male & female cases were almost the same. About where (40%) of cases were presented with rectal and ano-rectal lesions, the majority of cases (46.7%) had fungating tumor mass and (91.5%) of cases had Adenocarcinoma and (76.1%) of cases were of grade II by histological grading. Least percentage of metastatic cases was noticed in patients with rectal and ano-rectal masses (10.8-14.8%). About (50%) of patients were node negative by operation pathology, while 50% of patients were of pathological stage III. Conclusion: The present study demonstrated a high prevalence of CRC among the studied patients, advance stage at presentation of this type of cancer, high probability of recurrence, and it significantly correlated with poor survival.