Epidemiologic survey ongastroesophageal reflux disease in the population of Fujian province

Abstract

：Objective To assess theprevalence of gastroesophageal reflux disease(GERD) in the population of Fujian province,and to analyze the risk factors in relation to the disease. Methods A survey on GERDsymptoms and its related factors was carried out in the population of Fuzhou city inFujian province using a stratified random sampling method. According to reflux diseasequestionnaire (RDQ) score, the subjects were divided to GERD group with Sc≥ 12 and control group with Sc＜ 12.The risk factors related to GERD were compared between two groups. Results Atotal of 1347residents were investigated. The prevalence of GERD was 8.76 %, and male tofemale ratio wasincreased in population above 40 years of age (P＜0.05).The incidence of GERD in subjects with different occupations was as follows: thebusinessmen [17.91%(12/67)], retirees [13.48%(12/89)]and soldiers [2.94%(2/68)]. Symptomsincluding abdominal distension, belching, nausea, vomiting,dyspepsia were common in GERDgroup compared to control group (P ＜ 0.01). Besides, thelaryngitis, pharyngitis and mouth ulcer were common in GERD group compared to controlgroup ( P＜0.05).The risk factors of GERD were eating greasy (OR= 1.589) and sweetmeat (OR=2.413),overeating (OR = 2.053), constipation (OR = 1.650), acridity food (OR = 1.366 ),coffee (OR =1.295), strong tea (OR= 1.362). Conclusions The prevalence of GERD is high inthe population of Fujian province, and many factors are closely related to reflux. Key words: Gastroesophageal reflux; Epidemiologic studies; Fujian