Epidemiologic features and risk of scarring in pediatric patients with kerion celsi.

Abstract

Kerion celsi represents the inflammatory extreme of tinea capitis, as a delayed hypersensitivity reaction to the causative dermatophyte. Data regarding prevalence, trends in pathogens, and risk factors for scarring are limited. The main objective of the study is to assess clinical and epidemiologic features of children with kerion celsi and risk factors for scarring. We reviewed medical records of pediatric patients with kerion celsi treated between January 2006 and July 2020. Among 80 patients, the prevalence of permanent alopecia was 27.5%. Patients with remaining alopecia presented to our clinic at a mean 1.3months earlier than those with complete response to treatment (2.2±2.1 and 3.4±4.8, respectively; p<.05). Patients of Ethiopian ethnicity were more represented than in the general population; however, scarring was observed in only 11% (p=0.08). Outcomes did not differ by pathogen, antifungal treatment prescribed, duration of treatment, or the use of prednisone or antibiotics. Scarring alopecia is a common complication of kerion celsi. Host innate immune response, pathogen virulence, and treatment timeline should be considered as possible variables affecting risk of scarring in the future studies.