Abstract
To study clinical infection and molecular epidemiological characteristics of Salmonella. Choleraesuis (S. Choleraesuis) and its drug resistance pattern were analyzed retrospectively based on big data of public health and laboratory surveillance and related literature both at home and abroad. The S. Choleraesuis is confirmed belong to a swine-adapted pathogen which can cause zoonosis among immunocompromised persons due to its highly invasive capacity. Livestock cultivation is probably the means by which S. Choleraesuis acquires drug resistance. Outbreaks or sporadic infections have been found in Thailand, Taiwan and the mainland of China over the past decades. In developed countries, the incidence and resistance rates are at very low levels, but people are susceptible to the disease and it is difficult to isolate S. Choleraesuis from stool samples, which are in consistent with the situation in Asia. It is essential for agricultural sector to take infection source control measures for the control of human and swine infections with S. Choleraesuis and drug resistance spread, and it is necessary to strengthen the capability building of laboratories at all levels to detect S. Choleraesuis. Experience on foodborne outbreaks investigation in developed countries is worth learning.
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