EPH62 Annual Burden of Non-COVID-19 Respiratory Tract Infections in the Pre- to Post- Pandemic Eras: Analysis from the Anlitiks’ All Payor Claims Database

Abstract

The current study aims to shed light on the overall burden of patients with RTIs in the pre- to post-COVID pandemic eras in the US. A retrospective, administrative claims database, cross-sectional analysis is underway using the open-source Anlitiks’ All Payer Claims (AAPC) database. Total burden of RTIs [ICD-9/10= 465.8x, 465.9x, J06.9 (LRTI); and J22 (URTI)], including annual incidence and prevalence rates, will be ascertained among adults aged ≥18 years with inpatient or outpatient claims for non-COVID RTIs, including all upper and respiratory infections from 01/11/2016 to 12/31/2021. The denominator population will consist of all eligible patients within each respective year of study. Annual impact of health resource utilization will also be investigated. All analyses will be conducted using our RapidAnalyzer ecosystem, based on SQL and R analytic platforms. Preliminary results demonstrate the following number of patients with infections in 2016, 2017, 2018, 2019, 2020, 2021 and 2022 (through September, 2022): 11,929,725, 13,650,181, 13,635,828, 13,295,812, 9,032,305, 10,188,512 and 6,001,566, respectively. Prevalence and incidence of rates of RTIs will be addressed using proportions and person-years. Though overall rates of non-COVID RTIs may have decreased, it is unclear if lower rates of testing for non-COVID RTIs, and consequently under-diagnosis of other RTIs may have occurred in the post-pandemic era. Results from this analysis will contribute to the growing body of understanding the prevalence of RTIs over time, utilizing the APCD and RapidAnalyzer platform.