Abstract
The US Environmental Protection Agency plans to revamp its Endocrine Disruptor Screening Program (EDSP), a 25-year-old effort to screen chemicals for their ability to disrupt estrogen, androgen, and thyroid hormonal systems. In a draft white paper released Jan. 19, the EPA says certain nonanimal methods can be used as alternatives to vertebrate animal screening tests. The EPA estimates that it costs industry about $1 million per chemical and takes up to 6 years to conduct the current battery of assays in the first tier of the EDSP. Six of the assays involve the use of animals. T he agency has so far ordered first-tier testing for a small fraction of the thousands of chemicals subject to the EDSP. It issued the first set of screening orders for 67 pesticides in 2009, and 4 years later it finalized a second set of 109 chemicals. Lawyers who work closely with the chemical
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