EP285: Hidden threats: Identifying genetic risks for cardiomyopathy complications in healthy pregnant women

Abstract

Peripartum and pregnancy-associated cardiomyopathies (PPCM/PACM) refer to cardiac dysfunction and failure with onset during or immediately following pregnancy. PPCM patients are most often without a previously identified cardiac diagnosis but are at risk of long-term and significant functional compromise. Studies suggest that 10-15% of PPCM cases were familial and mainly involved genes identical to those associated with dilated cardiomyopathy (DCM) unrelated to pregnancy.