Abstract
Low-dose CT screening of the chest in the high-risk population is the current standard of care for early detection of lung cancer. CT screening is invasive due to radiation exposure and carries the risk of unnecessary biopsies of benign tumors. Here, we demonstrate metabolic changes in sputum and exhaled breath condensate (EBC) obtained from the same early-stage non-small cell lung cancer (NSCLC) patients pre-and post-surgical resection (SR), proposing the individual metabolic signature as a noninvasive diagnostic tool.
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