Abstract
Microsatellite Instability (MSI) refers to the hypermutable state of cells as a consequence of DNA mismatch repair (MMR) deficiency. Identification of hypermutable tumors is clinically valuable for selecting patients suitable for immunotherapy treatment. These alterations in microsatellite sequences characterize hereditary nonpolyposis colorectal cancer, but they have been reported in other cancers. This study aims to evaluate the status of primary lung adenocarcinoma in Morocco.
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