Abstract
The optimal thoracic radiotherapy (TRT) dose and fractionation for LS-SCLC remains unclear in clinical practice. We conducted a meta-analysis to assess the efficacy and safety difference between definitive hyperfractionated TRT (HyperTRT) (1.1Gy-1.6Gy, twice daily, with a minimum of 4-6h between fractions), hypofractionated TRT (HypoTRT) (2.5-4.0Gy/fraction, once-daily) or conventional TRT (ConvTRT) (1.8-2.2Gy/fraction, once-daily).
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